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KMID : 1101020180430040099
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Journal of Oral Medicine and Pain
2018 Volume.43 No. 4 p.99 ~ p.111
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Sjogren's Syndrome: an Update on Diagnostic, Clinical, and Basic Aspects for Oral Medicine Specialists
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Lee Kyung-Eun
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Abstract
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Sjogren’s syndrome (SjS) is a common autoimmune disorder characterized by lymphocytic infiltration in the salivary and lacrimal glands, resulting in severe dry mouth or eyes. As a result, most of SjS patients suffer from oral dryness and can visit the department of oral medicine with or without diagnosis of SjS. Therefore, oral medicine specialists should know clues, which may indicate the diagnosis of SjS from the clinical and laboratory investigations. By the recent SjS criteria, SjS can be diagnosed by focus score, ocular staining, Schirmer’s test, unstimulated whole saliva flow rate, and anti-SSA/Ro antibodies. The aim of this article is to review the diagnostic criteria, clinical investigation, and basic aspect related to SjS and to make oral medicine specialists play an important role in the detection of emerging SjS.
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KEYWORD
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Biopsy, Oral medicine, Sjogren’s syndrome, SSA antibodies, Staining and Labeling, Xerostomia
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